Twitter - To seperate niches?

i am just starting to use twitter for my various projects. I have an account for my recruitment business that has been great for networking but that had a specific focus. As I've been expanding what I have been doing my account is getting more and more generalised.

So i have decided to split my accounts into the 3 that I was most talking about

1. Recruitment
2. Rugby
3. Writing (the one in my sig)

And whilst 2 and 3 are new they seem to be getting some followers and a lot more interaction than a general account was managing. there is of course some bleed between the subjects of the two but in the main they are pretty seperate from each other.

So a question for those who like to drive traffic from Twitter. Is it better to have a large general account with a larger amount of followers, but less targetted and with less interaction (and so less trust) but more people available to 'be driven'?

Or is it better to have small accounts with targetted followers and a lot of interaction and trust?

I'm still testing at the moment, but would love feedback from people who have used it more than me