Will you remove the inactive subscribers in aweber?

This can remove some time wasters, so it is efficient to get rid of them,

Funny, I'm trying to figure out how to extend my niche to China. It's the biggest place on earth for the kind of customers I want.

And I love Malaysia. Do you have a problem with there; it's rather wealthy in parts. Don't delete me if I sign up from there.

This bit of knowledge just saved me a bunch of money every month...thanks!

Before doing this I always send out a warning message that the link in the message needs to be clicked if they want to stay on my lists, give them a great free offer as an incentive.

Open rates and other viewing metrics are poor indicators of active subscribers which is why using a positive click is a better option.

Better to have a small list of fans than a large list of email addresses

Absolutely you should manage the health of your list regularly.
Not only will a bloated list cost you more on services that charge on database size or sends - but it will affect any analytics you are doing and make it harder to see the real effectiveness of your campaigns.

Unsubscribes should be removed from active lists automatically - and indeed then manually deleted if they will be counted/charged for.
Of course also removing undeliverable/bounced addresses is a no-brainer (mis-typed emails, fake emails, deleted accounts, etc) - again some systems will do this for you automatically.

For inactive or dormant subscribers, you need to decide on your own definition of inactive. No opens? No clickthroughs? Based on a time period or on a number of sends? It will all depend on how frequently you mail them and the nature of the content.

There are a number of reasons people become dormant.
- Were never interested, or became disinterested, in your content, but haven't got round to unsubscribing.
- The user is somewhat interested, but simply hasn't had a chance to look at your mails in the time period.
- Your mails are going into a spam folder and not being seen.
- The email account was abandoned but not closed.

Personally I recommend a reach-out email to try and tempt back these people. Explain that you'll be removing them if you still hear nothing. Perhaps offer them a freebie or discount to tempt them back.

This email nears a very well thought out subject line, and well worded content. Do everything you can to ensure it isn't going to get marked as spam.

Finally, I would also say that your list shrinkage should be part of any analytics you perform. The list size is important, but doesn't tell the whole story (e.g. if you remove 50 people and gain 50 people in the same month, the size won't change). If you find the number of people you are purging is on the rise, then you might want to look at how engaging your content is, and how targetted your sign-up forms are, etc.

Hope this helps!