First of all, this is intended for people with their own products (although I'm sure it can be used in some way if you're an affiliate).
What I'm recommending, essentially, is making use of one of the "live chat" services. I put it on one of my sales pages a couple of weeks ago (a sales page that only subscribers are sent to, not cold traffic), and for an hour or two most days I send an invite to anyone who hangs around on my site for more than a few minutes.
The number of people who chose to buy my product during these couple of hours each day, after some one-on-one time, was amazing to me.
You can instantly reassure them in any areas where they feel uncomfortable, and some people who would clearly have left without ordering have gone ahead and made the purchase, happily.
As a bonus, you get to rewrite your salesletter based on the questions that are asked in the live chats, because you'll start to see patterns of problems that people are having that cause them not to buy.
I've even taken things one step further. This week, I sent out a broadcast email just to those who had subscribed in the past 7 days, and I told them that for the next couple of hours I would be available live on my website.
As soon as people arrived I sent them an invite, and from around 90 people who came and accepted the chat invite, 7 of them bought my product. And these were people who'd seen my sales page several times and had not purchased.
This may or may not be right for your buisness/products, but I thought I'd pass it along. It's something that you rarely see used in this way, and I think a lot of people are missing out on its potential.
It also works like a crash course in marketing/selling, because you learn very quickly what language your potential customers use, and how they like to be spoken to.
If you want to give it a try, you can go for the option I went with: live2support. I honestly don't know how good they are compared to the others who offer this service. I chose them purely because they have a 14 free trial that doesn't even require credit card info to be entered.
One final thing for anyone who wants to try this: I choose to remove the code from my pages when I'm not available to talk, because I don't want the distraction of a "currently offline" box there for someone who would otherwise buy.
Obviously the downside to this is the time it takes you to interact with many people individually, but you'll have to decide if that's right for you or not. But I know this: I never make 7 sales in an hour of a single product, but I did doing this.
If you try this, I'd love to hear how it works for you.