My primary concern will be moving my sites away from traditional SEO and going for the more dynamic LSI model (Latent Semantic Indexing) as I believe in 12 months from now I will be very well positioned to profit from it.
On a secondary level I'm planning to introduce a lot more sound to my sites and making them more welcoming on a deep psychological level. Don't know if anyone has heard of binaural technology, but it is a way of using sound to make a person feel a specific feeling. I'm going to be testing that and seeing if it can increase conversions.
So what are your plans for the next 12 months? Any new concepts you are looking at? Or sites to keep an eye on?