Ok, I'll try to be as clear as possible.

I've got a domain name: mysite.com

I'd like to offer my service in different countries as well, but I don't want to host my service from different domain names. For example: mysite.es or mysite.fr

Instead I'd like my service to be available like this:

mysite.com/en/
mysite.com/ru/
mysite.com/fr/
and so on....

How do you host sites like this? Obviously if you want to provide efficiency you need a server in the target country, but can you point a server to a subdirectory?

What is the most efficient way (serverwise) for hosting if you want to maintain the subdirectory approach?

Thanks