I've been doing Adwords for awhile but mostly on autopilot so I've been trying to roll up my sleeves a bit more lately.

A few questions so I'll break them up:

One: I promote affiliate offers such as Clickbank. I don't put affiliate links directly on the page, but link to redirects elsewhere on my site with affiliate links built in which send people to the sales pages for the offers, will this count against my quality score of my page versus if I had none of these redirect links?

Two: Should I be optimizing a landing page based for the keywords I'm targeting in the ad? Or rather, would I receive a higher quality score if so?

Three: I use adwords on a variety of my sites. Some of my sites are targeted just for one niche whereas for example I have another review style site which has a central hub as the main page then I review products on limitless and disconnected niches on the subdomains. Would this account for why I'm receiving lower quality scores for one of these pages versus a domain which is solely devoted to selling offers in one niche? And if so, what's up with that?

Thanks !