I've been playing around with a simple but clever method I devised (not sure if anyone else is doing something similar) to help increase my adsense CTR over the last week, and the results have been great so far. I've managed to increase my CTR by 2-5% on the sites that I tested this method on. There is no guarantee it will work for you, but there is no harm in testing it out on your site(s).
It involves using Jump Links or Page Jumps. A jump link is a link on a page that allows you to jump to a certain section on that page. For instance: if you visit a page on Wikipedia you will see a Table of Contents (ToC), and when you click on one of the links within the ToC your browser jumps to that specific section on the Wiki page.
I place a jump link at the bottom of my content and below each subsection of a page (if the content is long). The link simply tells my visitor to "click to return to the top" (or something similar). When they click that link their browser jumps right to the top where my Adsense ads are, and they are effectively forced to view the ads on my page.
I usually place ads at the bottom of my content, but I tried this technique on sites where the bottom unit wasn't performing and I've been happy with the outcome so far.
If you like this technique - test it out and report your results here as I will be interested to see whether it works for you!
How to Create a Jump Link in Wordpress?
To Your Success!
Added: the method works best for longer articles (1000+ words). Ensure you have white spaces around your ad. I personally like to place my biggest adsense block directly under the first paragraph of content with a break under that paragraph and above the second paragraph.When the jump-link is clicked the ad is shown directly in the centre of the visitors screen.