Which version of Dreamweaver are you using?

The newer version use CSS by default instead of the old html font tags.

What tool you use does not matter as much as how the pages are layed out.

For best results design your site around a Theme and have each of your sub pages target one keyword phrase related to theme.

Create a sitemap that organizes the page links into catagories and link to site map on each page (maybe in the footer).

Doing this will give your site more respect in Google and avoid a lot of the negative aspects of a made for adsense site.

The sitemap will also make it much easier for Google to index all of the pages of your site. Once google finds and indexes one page, it will only have to follow one link to reach more of the rest of the pages of your site.