Since AdWords was launched in 2001, Google has expanded to image ads, video ads, and print ads, and has frequently been rumored to be entering radio and television. While many think that television ads (ala Spot Runner) could be Google’s next major move, they may be neglecting a potentially larger opportunity: in-game video game advertising.

Earlier this year Massive Incorporated, a video game advertising network, announced a landmark deal with Major League Baseball and 2K Sports...