Let's suppose it is near the end of the month and you have accumulated $1000, and want to transfer to your bank account so you can pay your rent. So you withdraw the $1000. Then let's suppose someone contests a payment for $50 a few hours later. Paypal can then reverse the $1000 withdrawal, and it doesn't go to your bank.
So my advice is you split into 2-3 withdrawals. For example, maybe you withdraw $300, $300 and $400. Then paypal can only reverse one of the withdrawals and you will be closer to paying you rent, etc.
This method only takes a few seconds more and won't leave you anticipating the bank deposit.